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Brigitte Kopp Selected Research

hellebrin

6/2013Structure-activity relationship analysis of bufadienolide-induced in vitro growth inhibitory effects on mouse and human cancer cells.
4/2013Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase.
4/2010Rapid structural identification of cytotoxic bufadienolide sulfates in toad venom from Bufo melanosticus by LC-DAD-MS(n) and LC-SPE-NMR.

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Brigitte Kopp Research Topics

Disease

13Neoplasms (Cancer)
09/2017 - 12/2003
4Breast Neoplasms (Breast Cancer)
05/2017 - 04/2010
4Inflammation (Inflammations)
07/2015 - 09/2012
3Pain (Aches)
01/2019 - 05/2013
3Heart Failure
06/2015 - 04/2010
3Leukemia
06/2015 - 05/2011
2Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
08/2015 - 01/2015
2Asthma (Bronchial Asthma)
05/2013 - 01/2012
2Sleep Initiation and Maintenance Disorders (Insomnia)
03/2012 - 02/2012
1Wounds and Injuries (Trauma)
01/2021
1Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
01/2021
1Lymphatic Metastasis
05/2017
1Genetic Translocation (Chromosomal Translocation)
08/2015
1Neoplasm Metastasis (Metastasis)
07/2015
1Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2014
1Type 2 Diabetes Mellitus (MODY)
11/2014
1Diabetes Mellitus
03/2014
1Skin Diseases (Skin Disease)
05/2013
1Common Cold
05/2013
1Psychomotor Agitation (Akathisia)
02/2012
1Cardiovascular Diseases (Cardiovascular Disease)
01/2012
1Hand-Foot Syndrome
01/2007

Drug/Important Bio-Agent (IBA)

3Pharmaceutical PreparationsIBA
05/2017 - 01/2012
3Adenosine Triphosphatases (ATPase)IBA
06/2015 - 04/2013
3hellebrinIBA
06/2013 - 04/2010
2Proteins (Proteins, Gene)FDA Link
08/2015 - 10/2009
2Anaplastic Lymphoma KinaseIBA
08/2015 - 01/2015
2Methylene Chloride (Dichloromethane)IBA
07/2015 - 04/2009
2Cardiac GlycosidesIBA
06/2015 - 04/2013
2CardenolidesIBA
06/2013 - 04/2013
2hellebrigeninIBA
06/2013 - 04/2013
2BufanolidesIBA
06/2013 - 04/2013
2GABA-A Receptors (GABA(A) Receptor)IBA
03/2012 - 02/2012
2Amphibian VenomsIBA
09/2010 - 04/2010
2chan su (ChanSu)IBA
09/2010 - 04/2010
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
01/2021
1Ion Channels (Ion Channel)IBA
01/2019
1Eudesmane SesquiterpenesIBA
09/2017
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
05/2017
1Fenofibrate (CiL)FDA LinkGeneric
05/2017
1Biomarkers (Surrogate Marker)IBA
05/2017
1LactonesIBA
08/2015
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
08/2015
1SesquiterpenesIBA
08/2015
1Messenger RNA (mRNA)IBA
08/2015
1Pyridinolcarbamate (P23)IBA
08/2015
1CarrageenanIBA
07/2015
1PO-1IBA
07/2015
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2015
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2015
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
11/2014
1PPAR gammaIBA
03/2014
1Transcription Factors (Transcription Factor)IBA
03/2014
1Lycii Radicis CortexIBA
03/2014
1NF-kappa B (NF-kB)IBA
03/2014
1gamabufotalinIBA
06/2013
1Digoxin (Digitek)FDA LinkGeneric
06/2013
1Ouabain (G Strophanthin)IBA
06/2013
1bufotalinIBA
06/2013
1bufadienolideIBA
06/2013
1PoisonsIBA
05/2013
1Lactic Acid (Lactate)FDA LinkGeneric
04/2013
1LipidsIBA
09/2012
1Estrogen ReceptorsIBA
09/2012
1Cytochrome P-450 CYP1A1 (CYP1A1)IBA
09/2012
1Estrogens (Estrogen)FDA Link
09/2012
1SphingolipidsIBA
09/2012
1Butyric Acid (Butanoic Acid)IBA
03/2012
1gamma-Aminobutyric Acid (GABA)IBA
03/2012
1Plant ExtractsIBA
02/2012
1abnormal Savda MunziqIBA
01/2012
1Plant Preparations (Preparation, Plant)IBA
01/2012
1CalciumIBA
05/2011
1ikarugamycinIBA
05/2011
1p38 Mitogen-Activated Protein KinasesIBA
05/2011
1Antineoplastic Agents (Antineoplastics)IBA
05/2011
1ethyl acetateIBA
04/2010
1Cyclin D1IBA
10/2009
1Paclitaxel (Taxol)FDA LinkGeneric
10/2009
1Capecitabine (Xeloda)FDA Link
01/2007

Therapy/Procedure

4Therapeutics
01/2021 - 12/2003
2Chinese Traditional Medicine (Traditional Chinese Medicine)
08/2014 - 03/2014
1Drug Therapy (Chemotherapy)
01/2015
1Traditional Medicine (Folk Remedies)
05/2013
1Phytotherapy (Herbal Therapy)
01/2007
1Baths
01/2007